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Blebbistatin paradoxically induces ROCK-dependent junctional enrichment of p-MLC and adherens junction components in chick embryo epidermis

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The phosphorylation level of myosin light chain (p-MLC) is widely employed as a biochemical surrogate for cellular contractility in tissue mechanics studies, while small-molecule inhibitors such as Blebbistatin are routinely used to suppress non-muscle myosin ... ...