The Effect of Food and the Proton Pump Inhibitor Rabeprazole on Binimetinib Pharmacokinetics in Healthy Participants
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Background: Binimetinib is a selective and potent MEK1/MEK2 inhibitor approved in combination with encorafenib for patients with BRAF-mutant melanoma and non-small cell lung cancer. Binimetinib is a basic amine with pH-dependent ... ...
