Highly Conserved Core Residues Define Old-World Alphaviruses and Trace Early Evolutionary Divergence
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Alphaviruses are positive-sense, single-stranded RNA viruses that assemble into striking double-icosahedral particles. During budding, the nucleocapsid core forms in the cytoplasm and adopts a T = 4 icosahedral symmetry, a hallmark characteristic of Alphavirus... ...
