Alternate-Day Fasting Enhances Leptin Sensitivity via JMJD3-Dependent Epigenetic Regulation of the Leptin Receptor in the Hypothalamus
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Leptin resistance is a hallmark of obesity. It is characterized by diminished responsiveness to leptin and disrupts energy homeostasis. While multiple pathways contribute to leptin resistance, the transcriptional repression of the leptin receptor (LepRb) is a ... ...