Human GBP4 promotes TRIM21-BIP-dependent autophagy to restrict M. tuberculosis infection by preventing SORT1-mediated progranulin degradation
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Interferons (IFNs) are potent antimicrobial cytokines. However, effector mechanisms mediating their function in humans are poorly understood, partly because IFNs can induce numerous effector molecules. While guanylate-binding proteins (GBPs) are IFN-inducible,... ...
