Prevention of appearance of severe Huntington's disease symptoms in the R6/1 mouse model by early administration of 4',5,7-trihydroxyisoflavone
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BackgroundRecent reports indicated that 4',5,7-trihydroxyisoflavone (genistein) can improve biochemical disorders and correct behavioral disturbances in cellular and animal models of Huntington's disease (HD), acting thorough stimulation of autophagy-depende... ...
