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The potential of targeted IL-4 therapy for the comorbidity of atopic dermatitis and attention-deficit/hyperactivity disorder in children via the skin-brain axis

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Although Atopic Dermatitis (AD) and Attention-Deficit/Hyperactivity Disorder (ADHD) frequently coexist in children, the underlying mechanisms remain unclear. The "Skin-Brain Axis"(SBA) hypothesis, based on the shared ectodermal origin of the skin and the cen... ...