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Tumor suppressor BAP1 emerges as a key regulator of metabolism and cell death in tumors

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BRCA1-associated protein 1 (BAP1) is a deubiquitinase (DUB) localized in both the nucleus and cytoplasm and is widely recognized as a tumor suppressor. Germline and somatic alterations in BAP1 have been strongly associated with increased susceptibility to dive... ...