Podophyllotoxin induces testicular toxicity via the microbiota-gut-testis axis based on the toxicological evidence chain concept
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Podophyllotoxin (PPT), a natural lignan with well-established antitumor efficacy and well-documented ovarian toxicity, was first investigated for its potential testicular toxicity in male Sprague-Dawley rats, following the guidance of the Toxicological Evidenc... ...
