Effect of high mobility group box-1 on receptor for advanced glycation endproducts (RAGE) and toll-like receptor-4 (TLR4) diffusion and signaling
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High mobility group box-1 (HMGB1) is a damage-associated molecular pattern (DAMP) and a ligand for multiple immune receptors, including receptors for advanced glycation endproducts (RAGE) and toll-like receptor 4 (TLR4). Binding of HMGB1 to these receptors ini... ...
