Broad and durable protection against SARS-CoV-2 and SARS-CoV by an intranasal chimpanzee adenovirus vaccine expressing tandem RBDs and nucleocapsid
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Current intramuscular COVID-19 vaccines reduce severe disease but offer limited protection against infection, enabling viral persistence, immune escape, and transmission. We developed intranasal rare-serotype chimpanzee adenovirus 68 (AdC68)-based vaccines exp... ...
