Evaluation of the cellular impact of missense variants in low-density lipoprotein receptor-related protein 6 (LRP6) associated with cardiovascular diseases in HeLa and HEK293T cell lines
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Low-density lipoprotein (LDL) receptor-related protein 6 (LRP6) is crucial for the canonical wingless signaling pathway and the clearance of LDL from the bloodstream. Genetic variants in the LRP6 gene have been conclusively associated with cardiovascular disea... ...
