Distinct DNA hydroxymethylation landscape and mitochondrial DNA rearrangement signatures induced by single- and multi-fraction alpha particle radiation in lung fibroblasts
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Alpha (α)-radiation is a genotoxic and epigenotoxic agent capable of increasing the risk of cancer and other diseases. DNA hydroxymethylation (DNAhm) can modulate gene expression and is considered an under-researched epigenetic event in ionizing radiation stu... ...