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Tracer Gas Physicochemical Properties Influence DLCO Measurements in Patients With Ventilation Heterogeneity

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Measurement of the lung diffusing capacity for carbon monoxide (DLCO) requires an inert tracer gas-traditionally helium (He)-to estimate alveolar volume (VA). However, alternative gases such as argon (Ar), sulfur hexafluoride (SF6), and methane (CH4) differ ma... ...