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The imprinted Peg3 gene is a potent regulator of the DNA methylome in trophoblast cells

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Paternally expressed gene 3 (Peg3) is an imprinted gene whose knockout (KO) causes placental and fetal growth deficits as well as maternal behavioral defects, but its molecular role remains poorly understood. Here, we report that Peg3-null trophoblast stem cel... ...