High-throughput development and scale-up of recombinant adeno-associated virus 5 anion-exchange chromatography for high-purity capsid separation
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Recombinant adeno-associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids. Among purification approaches, anion-exchange chromatography (AEX) has e... ...
