Conversion of artemisinin into novel unprotected N-alkylamine-11-azaartemisinins with enhanced antimalarial activity
{{output}}
Two novel azaartemisinin scaffolds N-ethanamine-11-azaartemisinin (EAZA) 10 and N-propanamine-11-azaartemisinin (PAZA) 11 were synthesized from artemisinin 1 on multigram scale in excellent yields without the need for further column chromatography purification... ...
