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PFOA promotes PMAIP1-MCL1 apoptotic vulnerability within a BHLHE41-associated macrophage regulatory architecture in atherosclerosis

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Perfluorooctanoic acid (PFOA), a legacy per- and polyfluoroalkyl substance (PFAS), has been associated with dyslipidemia and adverse cardiovascular phenotypes, yet the plaque-macrophage mechanisms that may connect exposure to lesion biology remain incompletely... ...