Cooperative IFN-γ and TLR9 signaling reprogram tumor-associated macrophages to enhance antitumor immunity in melanoma
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Tumor-associated macrophages (TAMs) often adopt immunosuppressive phenotypes that promote tumor progression and limit the efficacy of immunotherapy. Although Toll-like receptor 9 (TLR9) agonists and interferon-γ (IFN-γ) possess immunostimulatory properties, ... ...
