Unveiling the structural insights and inhibitory potential of coumarin-1,2,3-triazole hybrids against BACE1: a promising approach for Alzheimer's disease therapy
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Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by amyloid beta (Aβ) plaque accumulation, in which β-secretase (BACE1) plays a central role in the amyloidogenic pathway. Inhibition of BACE1 represents a promising therapeut... ...
