Discovery of isokurarinone as an ATCase-engaging lead with potent activity against methicillin-resistant Staphylococcus aureus
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The global proliferation of methicillin-resistant Staphylococcus aureus (MRSA) persists as a significant contributor to challenging infections, highlighting the urgent necessity for therapies that utilize novel mechanisms. Aspartate transcarbamoylase (ATCase),... ...
