Computationally guided design of bioactive nanostructures for targeted clearance of amyloid-β aggregates in Alzheimer's disease
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Targeted clearance of pre-existing amyloid-β (Aβ) aggregation remains a central challenge in Alzheimer's disease (AD) therapy. Here we report a computationally guided protein-gold hybrid nanostructure, Aβ3FTnAu, that integrates Aβ-recognition motifs into ... ...