Construction and Validation of a Model for Predicting Antidepressant Treatment Outcomes in Patients with Depression by Monitoring Both Paroxetine Plasma Concentration and Dynamic SIRT1 Expression in Peripheral Blood
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Background: Paroxetine efficacy cannot be accurately predicted through TDM alone. Given SIRT1's linkage to drug response, we explored the predictive value of combined TDM and SIRT1 detection.Methods: In total, 27 treatment-naive... ...