Lactiplantibacillus plantarum NCHBL-004 improves intestinal motility and modulates serotonergic gene expression in a loperamide-induced constipation model
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Slow-transit constipation (STC) is characterized by reduced colonic motility, impaired smooth muscle function, and altered mucosal signaling. Among these pathways, mucosal serotonin (5-HT), mainly produced by enterochromaffin cells, contributes to intestinal m... ...
