The Nicotinamide Salvage Pathway is a Metabolic Vulnerability of High-Risk MDS Stem Cells
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High-risk myelodysplastic syndrome (HR-MDS) is a malignant clonal disorder originating in hematopoietic stem and progenitor cells (HSPCs). The current standard of care for HR-MDS patients has a poor response, thus necessitating exploration of vulnerabilities o... ...
