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Modulation of N-cadherin-mediated homophilic trans interaction upon direct binding of ADH-1: Exploring the molecular basis of action of ADH-1 as N-cadherin inhibitor

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Switching of cadherin expression patterns, as linked to epithelial-to-mesenchymal transition (EMT), is one of the most notable characteristics of cancer cell metastasis. Aberrant expression of N-cadherin, a cell adhesion protein, on tumour cells, has made this... ...