Deciphering the role of human thiol systems (Trx/Grx) in the transcriptional regulation: An emphasis on the role of thiol enzymes with the multifunctional APE1/Ref-1 enzyme in human health and diseases
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A thiol-dependent redox system exists in mammalian cells, which plays a critical role in maintaining the redox balance and protecting against oxidative damage. Thiol-containing proteins, which include glutaredoxin (Grx) and thioredoxin (Trx), are involved in r... ...
