Biomimetic nanosystem rewires microRNA-mediated inflammatory circuits and disrupts ROS crosstalk for multifaceted rheumatoid arthritis therapy
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Rheumatoid arthritis (RA) persists due to the intractable pro-inflammatory M1 macrophage phenotype, sustained by dysregulated cytokine/reactive oxygen species (ROS) production, where conventional single-target therapies fail to achieve durable M1-to-M2 repolar... ...
