Viral dsRNA drives hyperinflammatory but blunted antiviral responses with enhanced PD-L1 induction in a COPD-like airway epithelial model
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Programmed death-ligand 1 (PD-L1) suppresses T-cell activation during antiviral immune responses, and its expression is increased in airway epithelial cells after viral infection. Because chronic obstructive pulmonary disease (COPD) is characterized by excessi... ...