Pairing ampakine with brief hypoxia evokes phrenic neuroplasticity via a spinal NMDA receptor mediated mechanism
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Brief hypoxic episodes drive neuroplasticity in animal models and humans. Pretreatment with an allosteric AMPA receptor (R) modulator ("ampakine") enables a single hypoxic exposure to induce sustained increases in phrenic motor activity ("phrenic motor faci... ...