PARP1 safeguards nascent DNA from SMUG1-dependent processing of incorporated 5-hydroxymethyl-2'-deoxyuridine
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DNA base damage is the most common form of lesion, occurring approximately 10,000 times per cell a day. Such damage arises either from the incorporation of damaged nucleotides or from direct modification of bases within DNA strand. 5-hydroxymethyl-2´-deoxyuri... ...