α6GABAA receptor-selective positive allosteric modulator as a novel therapy for fibromyalgia: A proof-of-concept study in mice modeling chronic widespread musculoskeletal pain
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Fibromyalgia, a chronic pain disorder mainly due to central sensitization, remains an unmet medical need, as available treatments provide limited efficacy and are frequently associated with dose-limiting adverse effects. We previously developed pyrazoloquinoli... ...