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Induction of neutralising antibodies against conserved rhinovirus capsid protein VP4 is dependent on presentation of VP4 peptide immunogens in a virus-like conformation

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Infection with rhinovirus (RV) is a frequent cause of the common cold and is also associated with more significant morbidity, including hospitalisation, in people with chronic lung disease. At present, there is no licensed RV vaccine or antiviral. There are ov... ...