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Tumor-intrinsic TLR4 signaling as a context-dependent rheostat in glioblastoma

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Glioblastoma (GBM) remains resistant to therapy due to cellular heterogeneity and adaptive stress responses, yet the role of tumor-intrinsic Toll-like receptor 4 (TLR4) signaling in this process remains unresolved. This review addresses a central inconsistency... ...