Integrated docking-molecular dynamics, ADME-toxicity profiling, and transcriptomic validation identify oroxylin a as a TLR7-targeting flavonoid candidate in systemic lupus erythematosus
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Background: Systemic lupus erythematosus (SLE) remains difficult to control despite current therapies, highlighting the need for more selective, mechanism-based treatments targeting key innate immune components such as Toll-like ... ...