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Linking SIRT1 gene variation and protein levels to the pathophysiology of type 2 diabetes

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Sirtuin 1 (SIRT1), an NAD⁺-dependent deacetylase, is involved in glucose homeostasis, insulin signaling, and inflammatory regulation, making it a potential molecular target in type 2 diabetes mellitus (T2DM). This case-control study investigated the associati... ...