Dual-targeting oral nanoparticle mucosal vaccine against brucella infection: co-targeting M cells and dendritic cells
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This study designed and evaluated a chitosan nanoparticle-based mucosal vaccine (CS-CKS9-MEV-DCpep-NPs) targeting M cells and dendritic cells against Brucella. From four immunogenic outer membrane proteins (OMP10, Omp25, Omp31, BtpB), 41 specific epitope pepti... ...