TLR4-dependent upregulation of IL-22-producing T cells in the bone niche links to the imbalance of bone homeostasis
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Background: Toll-like receptor 4 (TLR4) activation within the bone marrow (BM) microenvironment regulates proinflammatory cytokines and chemokines, which influence immune activity and bone remodeling. However, the immune cell fac... ...
