The β2αB loop determines NAD(P) cofactor specificity and kinetics in trypanosomal D-3-hydroxy-butyrate dehydrogenases
{{output}}
Bacterial d-3-hydroxybutyrate dehydrogenases (HBDHs) catalyze the conversion between d-3-hydroxybutyrate and acetoacetate with NAD as the cofactor but not with NAD 2'-phosphate (NADP). However, HBDHs of the early-branched eukaryotic genus Trypanosoma utilize ... ...
