EXPRESS: Endothelial expression of human soluble epoxide hydrolase worsens acute microvascular and tissue injury after stroke in female mice with early-stage diabetes mellitus
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Female mice are protected from diabetes mellitus type 2 (DM2)-exacerbation of ischemic brain injury, concurrently expressing less soluble epoxide hydrolase (sEH), which degrades neuroprotective epoxyeicosatrienoates (EETs). We hypothesize that depleting EETs, ... ...
