Conformational Switching on Lipid Interfaces: Lessons from Refolding and Membrane Insertion of Diphtheria Toxin, BCL-2 Apoptotic Regulators and pHLIP
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The conformational switching of a protein from its water-soluble conformation to its membrane-inserted conformation is critical for many cellular processes: cellular entry of bacterial toxins via escape from the endosome, apoptotic regulation by the Bcl-2 prot... ...