Computation-driven discovery of novel chromone derivatives for the treatment of triple-negative breast cancer via mTOR-targeted inhibition and triggering antitumor immunity
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Triple-negative breast cancer (TNBC) is a highly aggressive and heterogeneous subtype of breast cancer characterized by early metastasis, poor prognosis, and high recurrence rates. Targeting dysregulated PI3K/Akt/mTOR signaling and triggering anti-tumor immuni... ...
