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Discovery, Structural Characterization, and Preclinical Evaluation of Monoclonal Antibodies against Xylazine Poisoning

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Xylazine is a nonopioid sedative that has emerged as a major adulterant in the illicit drug supply, contributing to rising fatal overdoses across the United States. Xylazine toxicity is not reversed by naloxone, and there are no current FDA-approved therapeuti... ...