Pristimerin Suppresses Janus Kinase/Signal Transducers and Activators of Transcription Oncogenic Signaling To Drive Mitochondrial and Caspase-Dependent Apoptosis in Multiple Myeloma
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Multiple myeloma (MM) is a plasma cell malignancy characterized by uncontrolled clonal expansion within the bone marrow, and despite major therapeutic advances, it remains largely incurable. The identification of novel agents capable of overcoming apoptosis re... ...