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Selective Serotonin-1A Receptor Activation Elicits Antinociceptive Activity in the Knee Osteoarthritis and Plantar Incisional Postoperative Pain Models in Rats

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NLX-204 is a high selectivity/high efficacy agonist at serotonin 5-HT1A receptors, which are well-established modulators of pain processing. Here, we evaluated the analgesic activity of NLX-204 in two rat models of nociceptive/inflammatory pain: the monoiodoac... ...