Rational Engineering of a Sucrose Phosphorylase for Switchable Regioselective Synthesis of Antioxidant Gallic Acid α-Glucosides
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Gallic acid is a bioactive polyphenol with poor solubility and stability. Enzymatic α-glucosylation can address these limitations, but regioselective synthesis among multiple phenolic hydroxyls remains challenging. Here, we engineer a sucrose phosphorylase fr... ...