Redox-dependent mitochondrial dynamics: PLK1 couples glutathione metabolism to ROS-driven JNK and DUSP6 pathways in colorectal cancer
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Polo-like protein kinase 1 (PLK1) is aberrantly overexpressed in colorectal cancer (CRC) and promotes malignant progression. However, whether PLK1 contributes to redox adaptation remains unclear. Here, we identify PLK1 as a critical hub that integrates glutath... ...