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Serum Sirtuin 1 as a potential indicator of disease activity and severity in systemic lupus erythematosus patients

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The aetiology and pathophysiology of systemic lupus erythematosus (SLE), are yet unclear. Autoantibodies that target various organs and tissues are produced as a result of SLE patients' poor immunological tolerance. Sirtuin-1 (SIRT1) is a histone deacetylase ... ...