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Blocking hepatocyte retinoic acid signaling increases hepatic retinol-RBP4 secretion and disrupts vitamin A homeostasis in mice

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Vitamin A is an essential micronutrient with broad physiological roles. The liver is of central importance in whole-body vitamin A homeostasis, with hepatocytes distributing retinol to the rest of the body by secreting it in complex with RBP4 (Retinol-binding ... ...