Synthesis of Potent Vanin-1 Inhibitors Labelled With Carbon-14 and Deuterium
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Vanin-1 is an enzyme highly expressed in the kidneys, liver, and small intestines. Inhibition of this enzyme has been postulated as a novel approach in the treatment of several inflammatory diseases. BI 764122, BI 1585773, and BI 1595043 are very potent inhibi... ...